Optimized and validated spectrophotometric methods for the determination of amiodarone hydrochloride in commercial dosage forms using N-bromosuccinimide and bromothymol blue
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چکیده
منابع مشابه
Optimized and Validated Spectrophotometric Methods for the Determination of Enalapril Maleate in Commercial Dosage Forms
Four simple, rapid and sensitive spectrophotometric methods have been proposed for the determination of enalapril maleate in pharmaceutical formulations. The first method is based on the reaction of carboxylic acid group of enalapril maleate with a mixture of potassium iodate (KIO(3)) and iodide (KI) to form yellow colored product in aqueous medium at 25 +/- 1 degrees C. The reaction is followe...
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Two simple, sensitive and economical spectrophotometric methods have been developed for the determination of amiodarone hydrochloride in pure form and commercial dosage form. These methods (A and B) are based on the reaction of amiodarone base as n-electron donor with p-chloranilic acid and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as pi-acceptors to give highly colored complex species wh...
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Simple and sensitive spectrophotometric methods for the determination of midazolam (MID) are proposed. The methods are based on the bromination of the drug using N-bromosuccinimide (NBS) and the excess oxidant is determined by either malachite green (MG) or safranin O (SO), the absorbances of which are measured at 617 or 522 nm for MID-MG and MID-SO, respectively. Under the optimized experiment...
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Two spectrophotometric methods have been described for the assay of verapamil hydrochloride in drug formulations. Method A is based on the oxidation of the drug with potassium metaperiodate in sulfuric acid medium to give colored product, which absorbs maximally at 425 nm. Method B involves the formation of colored chloroform extractable ion-pair complex of the drug with tropaeolin 000 No.1 at ...
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Two simple, rapid, cost-effective and sensitive spectrophotometric procedures are proposed for the determination of hydroxyzine dihydrochloride (HDH) in pharmaceuticals and in spiked human urine. The methods are based on the charge transfer complexation reaction of the drug with either iodine (I2) as a σ-acceptor (method A) in dichloromethane or picric acid (PA) as a π-acceptor (method B) in ch...
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ژورنال
عنوان ژورنال: Journal of Saudi Chemical Society
سال: 2017
ISSN: 1319-6103
DOI: 10.1016/j.jscs.2013.09.001